Efficacy of urinary stone removal formula in the treatment of residual stones after kidney stone flexible ureteroscopy lithotripsy
Objective To explore the therapeutic effect of urinary stone removal formula on residual stones after flexible ureteroscopy lithotripsy(FURL)for kidney stones.Methods 86 patients with kidney stones were selected and divided into the control group and the observation group according to random number table method,with 43 cases in each group.The control group was treated with tamsulosin after FURL,while the observation group received the combination of urinary stone removal formula treatment on the basis of the treatment of the control group.Both groups were treated for 4 weeks.Clinical efficacy,the score of syndrome of dampness-heat diffusing downward before and after treatment,the levels of serum creatinine(Scr),cystatin C(Cys-C),blood urea nitrogen(BUN),β2-microglobulin(β2-MG),interleukin-6(IL-6),C-reactive protein(CRP),tumor necrosis factor-α(TNF-α)and interleukin-1β(IL-1β),and adverse reactions and the recurrence rate of stones in both groups were compared.Results After treatment,the score of syndrome of dampness-heat diffusing downward,and the levels of BUN,Scr,β2-MG,Cys-C,IL-6,IL-1β,TNF-α,and CRP were all reduced in both groups(P<0.05),and the observation group was lower than the control group(P<0.05);The stone clearance rate of the observation group was significantly higher than that of the control group[95.35%(41/43)vs.76.74%(33/43),P<0.05];The total effective rate of the observation group was higher than that of the control group[95.35%(41/43)vs.74.42%(32/43),P<0.05];There was no statistically significant difference in adverse reactions between two groups(P>0.05);The recurrence rate of stones in the observation group was lower than that in the control group[4.65%(2/43)vs.18.60%(8/43),P<0.05].Conclusion The combination of urinary stone removal formula and tamsulosin can promote the removal of residual stones after FURL,alleviate clinical symptoms,reduce inflammatory reactions in the body,protect renal function,and improve stone clearance rate.
万方数据
维普
