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肝胆管结石患者术后感染的危险因素及预防措施

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目的 探讨肝胆管结石患者术后感染的危险因素及预防措施.方法 回顾性纳入 2022 年 1 月—2023 年 12 月新疆医科大学第一附属医院行肝部分切除术的 118 例肝胆管结石患者,分为感染组与未感染组,各 59 例,检测并分析患者病原菌感染情况和分布,Logistic回归分析肝胆管结石患者术后并发症的影响因素,构建列线图模型.结果 59 例术后感染患者感染部位包括切口、腹腔、尿路、肺部、膈下,其中切口占比最高,为42.37%.感染组年龄≥60 岁、糖尿病、胆肠吻合术、术前白蛋白<35 g·L-1、术中失血量≥400 mL、手术时间≥300 min比例高于未感染组(P<0.05).年龄≥60 岁、有糖尿病、胆肠吻合术、术前白蛋白<35 g·L-1、术中失血量≥400 mL、手术时间≥300 min是肝胆管结石患者肝部分切除术后感染性并发症发生的危险因素(P<0.05).列线图模型实际概率与预测概率一致性较高,可有效预测并发症发生风险.结论 肝胆管结石患者肝部分切除术后感染性并发症发生的危险因素包括年龄≥60 岁、患糖尿病、胆肠吻合术、术前白蛋白<35 g·L-1、术中失血量≥400 mL、手术时间≥300 min,对于合并相关危险因素的患者需采取针对性预防措施,降低术后感染发生率.
Risk factors and preventive measures for postoperative infection in patients with hepatolithiasis
Objective To explore risk factors and preventive measures for postoperative infection in patients with hepatolithiasis.Methods 118 patients with hepatolithiasis who underwent partial hepatectomy in the First Affiliated Hospital of Xinjiang Medical University from January 2022 to December 2023 were retrospectively enrolled and divided into the infection group and the non infection group,with 59 cases in each group.The infection status and distribution of pathogens in patients were detected and analyzed.Logistic regression analysis was used to analyze the influencing factors of postoperative complications in patients with hepatolithiasis.The nomogram model was constructed.Results Among 59 postoperative infectious patients,the infection sites included incisions,abdominal cavity,urinary tract,lungs,and diaphragm,with incisions accounting for the highest proportion at 42.37%.The proportion of patients with age≥60 years,diabetes,choledochojejunostomy,preoperative albumin<35 g·L-1,intraoperative blood loss≥400 mL,and operation time≥300 min in the infection group was higher than that in the non infection group(P<0.05).Age≥60 years,diabetes,choledochojejunostomy,preoperative albumin<35 g·L-1,intraoperative blood loss≥400 mL,and operation time≥300 min were risk factors for infectious complications after partial hepatectomy in patients with hepatolithiasis(P<0.05).The nomogram model had a high consistency between the actual probability and the predicted probability,which could effectively predict the risk of complications.Conclusion The risk factors of infectious complications after partial hepatectomy in patients with hepatolithiasis include age≥60 years,diabetes mellitus,choledochojejunostomy,preoperative albumin<35 g·L-1,intraoperative blood loss≥400 mL,and operation time≥300 min.Targeted preventive measures should be taken for patients with combined risk factors to reduce the incidence of postoperative infections.

hepatolithiasispartial hepatectomyinfectionrisk factor

纽燕娜、赵萍、魏婷、朱翊、马蕊谦、张阳

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新疆医科大学第一附属医院,乌鲁木齐 830054

肝胆管结石 肝部分切除术 感染 危险因素

2024

长春中医药大学学报
长春中医药大学

长春中医药大学学报

CSTPCD
影响因子:0.916
ISSN:1007-4813
年,卷(期):2024.40(12)