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儿童及青少年1型糖尿病患者维生素D缺乏现状及影响因素分析

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目的:调查儿童及青少年1型糖尿病(T1DM)患者维生素D缺乏的现状并分析其影响因素.方法:收集2021年1月至2022年11月某医院小儿内分泌科住院179例T1DM患者的临床资料,统计儿童及青少年T1DM患者发生维生素D缺乏的情况,采用logistic回归分析其影响因素.结果:179例住院儿童及青少年T1DM患者发生维生素D严重缺乏34例(18.99%),维生素D缺乏79例(44.13%),维生素D不足54例(30.17%),维生素D充足12例(6.70%).年龄、民族、入院时是否为糖尿病酮症酸中毒及检测季节是儿童及青少年T1DM患者维生素D缺乏的影响因素(P<0.05).结论:儿童及青少年T1DM患者维生素D缺乏发生率高,尤其是7岁以上的T1DM患者.应针对其影响因素采取相应预防措施,以降低维生素D缺乏的发生风险.
Current status of vitamin D deficiency and its influencing factors in children and adolescents with type 1 diabetes mellitus
Objective:To investigate the current status of vitamin D deficiency in children and adolescents with type 1 diabetes mellitus(T1DM)and analyze its influencing factors.Methods:Clinical data of 179 T1DM patients admitted to the Pediatric Endocrinology Department of a hospital from January 2021 to November 2022 were collected.The status of vitamin D deficiency in children and adolescents with T1DM was statistically analyzed,and its influencing factors were analyzed using logistic regression.Results:Among 179 hospitalized children and adolescents with T1DM,34 cases(18.99%)had severe vitamin D deficiency,79 cases(44.13%)had vitamin D deficiency,54 cases(30.17%)had insufficient vitamin D,and 12 cases(6.70%)had sufficient vitamin D.Age,nationality,whether it was diabetes ketoacidosis at admission and the testing season were the influencing factors of vitamin D deficiency in children and adolescents with T1DM(P<0.05).Conclusion:The incidence of vitamin D deficiency is high in children and adolescents with T1DM,especially in those over 7 years old.Corresponding preventive measures should be taken based on the influencing factors in order to reduce the risk of vitamin D deficiency.

childrenadolescentstype 1 diabetes mellitusvitamin Dinfluencing factors

杨鑫、林梦、余爽

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四川大学华西第二医院小儿遗传代谢内分泌护理单元,四川成都 610000

出生缺陷与相关妇儿疾病教育部重点实验室,四川成都 610000

儿童 青少年 1型糖尿病 维生素D 影响因素

四川省心理学会年度科研规划项目

SCSXLXH2022008

2024

现代临床医学
成都市医学信息所,成都医学会

现代临床医学

影响因子:0.895
ISSN:1673-1557
年,卷(期):2024.50(3)
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