成都市喘息婴幼儿呼出气一氧化氮水平与大气污染物浓度的相关性
Correlations between the levels of fractional exhaled nitric oxide and the concentrations of atmospheric pollutants in wheezing infants and young children in Chengdu
段亚平 1周珈旭 1艾涛 1张蕾 1姚佳伟 1罗荣华1
作者信息
- 1. 电子科技大学医学院附属妇女儿童医院·成都市妇女儿童中心医院,四川成都 610000
- 折叠
摘要
目的:探讨喘息婴幼儿呼出气一氧化氮(FeNO)水平与大气污染物浓度的相关性.方法:回顾性分析2019年1-12月在我院就诊且有喘息患儿的临床资料,根据不同年龄分为婴儿组(＜12个月,1783例)和幼儿组(12～36个月,2354例),进行FeNO检测.收集成都市环境监测部门和气象局2019年1-12月每月PM2.5、PM10、二氧化硫(SO2)、二氧化氮(NO2)、臭氧(O3)、一氧化碳(CO)和气象数据,并分析喘息婴幼儿FeNO水平与大气污染物浓度的相关性.结果:幼儿组喘息发生率、FeNO值均高于婴儿组(P＜0.05).婴幼儿FeNO值与PM2.5、PM10、SO2、NO2浓度均呈正相关,与O3浓度及平均气温水平呈负相关(P＜0.05).结论:成都市喘息婴幼儿的FeNO水平与大气污染物浓度存在紧密的相关性,应告诫患儿家长在空气污染较重时减少外出,并持之以恒地推进大气污染综合整治.
Abstract
Objective:To exploring the correlations between the levels of fractional exhaled nitric oxide(FeNO)and the concentrations of atmospheric pollutants in wheezing infants and young children.Methods:A retrospective analysis was conducted on the clinical data of children with wheezing who visited our hospital from January to December 2019.According to different ages,they were divided into infant group(＜12 months,1783 cases)and toddler group(12-36 months,2354 cases)for FeNO testing.Monthly PM2.5,PM10,SO2,NO2,O3,CO,and meteorological data were collected from the Chengdu Environmental Monitoring Department and Meteorological Bureau from January to December 2019.The correlations between FeNO levels in wheezing infants and young children and the concentrations of atmospheric pollutants were analyzed.Results:The incidence of wheezing and FeNO value in the toddler group were higher than those in the infant group(P＜0.05).The FeNO value of infants and young children was positively correlated with PM2.5,PM10,SO2,NO2 concentrations,and negatively correlated with O3 concentration and average temperature level(P＜0.05).Conclusion:There are close correlations between the FeNO levels of wheezing infants and young children in Chengdu and the concentrations of atmospheric pollutants.Parents of these children should be advised to reduce their outdoor activities when air pollution is severe.Moreover,air pollution control should be persistently promoted.
关键词
喘息/婴幼儿/呼出气一氧化氮/二氧化氮/一氧化碳/二氧化硫/臭氧Key words
wheezing/infants and young children/fractional exhaled nitric oxide/nitrogen dioxide/carbon monoxide/sulfur dioxide/ozone引用本文复制引用
出版年
2024
NETL
NSTL
万方数据