Correlations between the levels of fractional exhaled nitric oxide and the concentrations of atmospheric pollutants in wheezing infants and young children in Chengdu
Objective:To exploring the correlations between the levels of fractional exhaled nitric oxide(FeNO)and the concentrations of atmospheric pollutants in wheezing infants and young children.Methods:A retrospective analysis was conducted on the clinical data of children with wheezing who visited our hospital from January to December 2019.According to different ages,they were divided into infant group(＜12 months,1783 cases)and toddler group(12-36 months,2354 cases)for FeNO testing.Monthly PM2.5,PM10,SO2,NO2,O3,CO,and meteorological data were collected from the Chengdu Environmental Monitoring Department and Meteorological Bureau from January to December 2019.The correlations between FeNO levels in wheezing infants and young children and the concentrations of atmospheric pollutants were analyzed.Results:The incidence of wheezing and FeNO value in the toddler group were higher than those in the infant group(P＜0.05).The FeNO value of infants and young children was positively correlated with PM2.5,PM10,SO2,NO2 concentrations,and negatively correlated with O3 concentration and average temperature level(P＜0.05).Conclusion:There are close correlations between the FeNO levels of wheezing infants and young children in Chengdu and the concentrations of atmospheric pollutants.Parents of these children should be advised to reduce their outdoor activities when air pollution is severe.Moreover,air pollution control should be persistently promoted.
wheezinginfants and young childrenfractional exhaled nitric oxidenitrogen dioxidecarbon monoxidesulfur dioxideozone
NETL
NSTL
万方数据
