摘要
目的:探究白蛋白与球蛋白比率(AGR)在输尿管镜碎石术(URS)术后并发发热性尿路感染(UTI)早期诊断中的价值.方法:回顾性分析2021年5月至2022年12月在我院行URS的280例患者的临床资料,根据是否发生发热性UTI分为感染组(78例)与未感染组(202例).比较两组AGR、CRP及PCT水平,采用ROC曲线分析AGR、CRP及PCT对URS术后患者并发发热性UTI的诊断价值.结果:感染组AGR、CRP及PCT水平均高于未感染组(P＜0.05).AGR、CRP、PCT及联合诊断的曲线下面积分别为0.729、0.836、0.841及0.943,均具有诊断价值,且联合诊断的价值高于各指标单独诊断(P＜0.05).AGR≥1.51、CRP≥79.6 mg/L、PCT≥1.6 µg/L、合并糖尿病、合并慢性肾功能不全、手术时间≥90 min及结石大小≥3 cm为URS术后并发发热性UTI的独立危险因素(P＜0.05).结论:AGR可有效早期诊断URS术后并发发热性UTI,URS术后并发发热性UTI的独立危险因素较多,临床应引起重视,并根据危险因素进行针对性干预.
Abstract
Objective:To explore the value of albumin to globulin ratio(AGR)in the early diagnosis of febrile urinary tract infection(UTI)after ureteroscopic lithotripsy(URS).Methods:A retrospective analysis was conducted on the clinical data of 280 patients who underwent URS in our hospital from May 2021 to December 2022.They were divided into an infected group(78 cases)and an uninfected group(202 cases)based on whether febrile UTI occurred.The levels of AGR,CRP,and PCT was compared between the two groups,and ROC curve analysis was used to evaluate the diagnostic value of AGR,CRP,and PCT for febrile UTI in patients after URS.Results:The levels of AGR,CRP,and PCT in the infected group were higher than those in the uninfected group(P＜0.05).The areas under the curve of AGR,CRP,PCT,and combined diagnosis were 0.729,0.836,0.841,and 0.943,respectively,which indicated all of them had diagnostic value.The independent risk factors for febrile UTI after URS were AGR≥1.51,CRP≥79.6 mg/L,PCT≥1.6 μg/L,complicated with diabetes,complicated with chronic renal insufficiency,operation time≥90 min,and stone size≥3 cm(P＜0.05).Conclusion:AGR can effectively diagnose febrile UTI after URS in the early stage.There are many independent risk factors for febrile UTI after URS.Clinical attention should be paid to take targeted intervention measures based on these risk factors.
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万方数据