Value of serum S-100β,BUN combined with APACHE Ⅱ score in evaluating the prognosis of elderly patients with sepsis
Objective:To explore the value of serum S-100β,BUN combined with APACHE Ⅱ score in evaluating the prognosis of elderly patients with sepsis.Methods:102 elderly patients with sepsis admitted to Xinyu Beihu Hospital from April 2022 to June 2023 were selected.They were divided into mild,moderate,and severe groups based on the APACHE Ⅱ score.Meanwhile,they were divided into a good prognosis group and a poor prognosis group using the modified Rankin scale.The differences in S-100β,BUN,and APACHE Ⅱ score were compared among the groups.The correlations between S-100β,BUN,and APACHE Ⅱ score were analyzed as well as the value of the three in evaluating the prognosis of elderly sepsis patients.Results:The S-100β,BUN,and APACHE Ⅱ score of the severe group were higher than those of the moderate and mild groups;the S-100β,BUN,and APACHE Ⅱ score of the poor prognosis group were higher than those of the good prognosis group(P＜0.05);S-100β and BUN were positively correlated with APACHE Ⅱ score(r=0.458,0.479,P＜0.05);ROC analysis showed that the area under the curve of S-100β,BUN combined with APACHE Ⅱ score in evaluating the prognosis of elderly sepsis patients was 0.928,which was higher than that evaluated by the three alone.Conclusion:The combination of S-100β,BUN,and APACHE Ⅱ score has relatively high value in evaluating the prognosis of elderly patients with sepsis.
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