首页|DETECTION OF CHROMOSOME ABERRATIONS IN TWELVE PRIMARY GASTRIC CANCERS BY DIRECT CHROMOSOME ANALYSIS AND FISH
DETECTION OF CHROMOSOME ABERRATIONS IN TWELVE PRIMARY GASTRIC CANCERS BY DIRECT CHROMOSOME ANALYSIS AND FISH
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Direct chromosome analysis and FISH were performed on twelve primary gastric carcinomas. Two of them had simple chromosome changes: 48,XX, +8, +20, and 49, XY, +2, +8, +9, and the others had complicated chromosome changes, which includes much more numerical and structural chromosome aberrations. Frequent structural changes in the complicated types involved chromosome 7, 3, 1, 5 and 12 etc. The del 7q was noted in eight cases. The del (3p) and del (1p) were noted in six and five cases, respectively. The results provide some important clues for isolation of the genes related to gastric cancer.
gastric cancerchromosome changescytogeneticsFISH
Xia Jianchuan、Lu Song、Zhang Jianhua、Ning Xiaoming、Liu Quanzhang、Li Pu
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Laboratory of Medical Genetics, Basic Medical College of Harbin Medical University, Harbin 150086
Department of Pathology, Tumor Hospital of Harbin Medical University, Harbin 150040
Department of Biochemistry, Gannan Medical College, Gannan 341000
NETL
NSTL
万方数据
维普
