治疗血管钙化的良方何觅
Vascular Calcification:Where is the Cure?
刘雯雯 1刘梅林1
作者信息
- 1. 北京大学第一医院老年病内科,西城区 100034,北京市,中国
- 折叠
摘要
随着年龄的增长,血管钙化(vascular calcification,VC)的发病率逐渐升高,导致相关心血管事件和全因死亡增加,加重了全球临床负担.在过去的几十年里,针对VC发病机制的陆续研究为VC的治疗提供了一些可能性.然而,目前的干预手段都未能在逆转或治愈VC方面取得肯定的临床效果.本文旨在总结干预VC的新发现,为临床治疗提供参考.
Abstract
With the progress of aging,the incidence of vascular calcification(VC)gradually increases,which is correlated with cardiovascular events and all-cause death,aggravating global clinical burden.Over the past several decades,accumulating approaches targeting the underlying pathogenesis of VC have provided some possibilities for the treatment of VC.Unfortunately,none of the current interventions have achieved clinical effectiveness on reversing or curing VC.The purpose of this review is to make a summary of novel perspectives on the interventions of VC and provide reference for clinical decision-making.
关键词
血管钙化/临床/病理生理学/治疗策略/新发现Key words
vascular calcification/clinical/pathophysiology/therapeutic strategies/novel findings引用本文复制引用
基金项目
Peking University Baidu Fund(2019BD019)
出版年
2024
NETL
NSTL
万方数据