目的:开发并验证一种新型急性缺血性脑卒中(acute ischemic stroke,AIS)评分系统-前后循环梗死评分系统(anterior and posterior circulation infarction image score,APCIIS).方法:回顾性分析2020年6月至2021年6月在重庆医科大学附属第一医院收治的163例急性缺血性卒中患者的临床资料.将患者分为前循环AIS组(n=109)及后循环AIS组(n=54).利用单因素和多因素分析影响前循环AIS及后循环AIS患者预后情况的危险因素.以血栓负荷评分(the clot burden score,CBS)及基底动脉闭塞评分(the basilar artery on computed tomography angiography score,BATMAN)为参考,绘制受试者工作特征曲线,分析该新型评分(APCIIS)预后评估的价值.结果:在前循环AIS组,APCIIS的预后评估价值虽然未能优于CBS,但显示出相对更高的敏感度86.8%、特异度90.1%及曲线下面积0.939.在后循环AIS组,APCIIS的预后价值优于BATMAN评分.结论:APCIIS是预测急性缺血性脑卒中患者预后的1种方便可靠的办法.
Anterior and posterior circulation infarction image score(APCIIS),a novel approach to evaluate the prognosis of patients with acute ischemic stroke
Objective:Development and validation of a novel acute ischemic stroke(AIS)scoring system:Anterior and posterior circu-lation infarction image score(APCIIS).Methods:Retrospective analysis of clinical data from 163 patients with acute ischemic stroke admitted to the First Affiliated Hospital of Chongqing Medical University from 2020/6 to 2021/6.The patients were divided into ante-rior circulation AIS group(n=109)and posterior circulation AIS group(n=54).Univariate and multivariate analyses were performed to identify risk factors affecting the prognosis of patients with AIS.Using the Clot Burden Score(CBS)and the Basilar Artery on Com-puted Tomography Angiography score(BATMAN)as references,receiver operating characteristic(ROC)curves were plotted to analyze the predictive value of the novel scoring system(APCIIS)for prognosis assessment.Results:In the anterior circulation AIS group,although the prognostic value of APCIIS was not superior to CBS,it demonstrated relatively higher sensitivity of 86.8%,specificity of 90.1%,and an area under the curve of 0.939.In the posterior circulation AIS group,APCIIS showed better prognostic value than the BATMAN score.Conclusion:APCIIS is a convenient and reliable method for predicting the prognosis of patients with AIS.