Latent class analysis of behavioral characteristics of children with acute leukemia and associated influencing factors
Objective:To explore the potential categories of behavioral characteristics of children with acute leukemia using latent class analysis and associated influencing factors,and to provide evidence for developing precise intervention strategies for behavioral problems in children with leukemia.Methods:We selected 202 children with acute leukemia and their caregivers by convenience sam-pling in the Department of Hematology of Children's Hospital of Chongqing Medical University for a survey using the General Informa-tion Questionnaire,Rutter Child Behavior Questionnaire,General Family Functioning Scale,and Social Support Rating Scale.The be-havioral characteristics of children with acute leukemia were categorized using a latent class analysis,and the effects of various factors on different categories were analyzed using a multinomial logistic regression analysis.Results:TThe behavioral characteristics of chil-dren with acute leukemia were classified into three types:impulsive-unfriendly type(50%),emotional-somatic disorder type(33.66%),and well-behaved type(16.34%).The multinomial logistic regression analysis showed that unhealthy family functioning and male were more frequently associated with the impulsive-unfriendly type compared with the well-behaved type;unhealthy family functioning,male,and being in the treatment period were more frequently associated with the emotional-somatic disorder type compared with the well-behaved type;and children in the treat-ment period were prone to developing the impulsive-unfriendly type compared with the emotional-somatic disorder type.Conclusion:Children with acute leukemia have distinct types of behavioral features,which are closely related to family functioning,sex,and dis-ease stage.Therefore,for different behavioral types,targeted individualized interventions should be developed to prevent or reduce the occurrence of behavioral problems in children with acute leukemia,improving their social adaptability and quality of life.
acute leukemiachildrenlatent class analysissocial supportfamily functioningpediatric nursing