重庆医科大学学报2024,Vol.49Issue(5) :597-602.DOI:10.13406/j.cnki.cyxb.003500

多发性硬化的治疗进展

Advances in the treatment of multiple sclerosis

王茜 陆正齐 李蕊
重庆医科大学学报2024,Vol.49Issue(5) :597-602.DOI:10.13406/j.cnki.cyxb.003500

多发性硬化的治疗进展

Advances in the treatment of multiple sclerosis

王茜 1陆正齐 1李蕊1
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作者信息

  • 1. 中山大学附属第三医院神经内科,广州 510630
  • 折叠

摘要

多发性硬化(multiple sclerosis,MS)是 一种慢性中枢神经系统炎症性脱髓鞘疾病,随着人们对MS发病机制了解的深入,MS的治疗手段也在不断更新.近年来,新上市的疾病修饰治疗(disease-modifying therapy,DMT)药物层出不穷,临床研究显示出良好的疗效及安全性.治疗策略及目标也在更新.本文主要对近年来新上市的DMT药物的作用机制、疗效以及安全性进行综述,此外对治疗策略、治疗目标以及正在研发的新药也做了简要介绍,以期为临床决策的制定提供参考.

Abstract

Multiple sclerosis(MS)is a chronic inflammatory demyelinating disease of the central nervous system.As our understanding of the pathogenesis of MS gradually deepens,the treatment methods for MS are being constantly updated.In recent years,a large num-ber of disease-modifying therapy(DMT)drugs have been introduced,and clinical studies have shown that such drugs have good effi-cacy and safety.Treatment strategies and goals are also being improved.This article mainly reviews the mechanism of action,efficacy,and safety of the DMT drugs introduced in recent years and briefly introduces treatment strategies,treatment goals,and new drugs under development,in order to provide a reference for clinical decision-making.

关键词

多发性硬化/治疗/进展/疾病修饰治疗

Key words

multiple sclerosis/treatment/advances/disease-modifying therapy

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基金项目

国家自然科学基金(81901229)

出版年

2024
重庆医科大学学报
重庆医科大学

重庆医科大学学报

CSTPCD北大核心
影响因子:0.724
ISSN:0253-3626
参考文献量3
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