Current status and prospects of the prevention and treatment of kidney stones
Objective:To summarize the latest achievements in the prevention and treatment of kidney stones in recent years,to look forward to the prospects and development direction of the prevention and treatment of kidney stones,and to provide brand-new concepts for research on the prevention and treatment of kidney stones.Methods:PubMed,CNKI,and Wanfang Data were searched for articles on the prevention and treatment of kidney stones published within the past five years,and high-quality articles(40 clinical studies and 20 basic studies)were included.With reference to these studies and the experience and thoughts of our team,this article discusses the current status and prospects of research on the prevention and treatment of kidney stones.Results:In recent years,substantial achievements had been obtained for research on the prevention and treatment of kidney stones.Related clinical studies mainly focused on the composition of kidney stones,lithotripsy procedures and equipment for kidney stones,and pharmacotherapy for kidney stones,while basic studies mainly focused on crystal-mediated renal tubular epithelial cell damage,immune cell regulation,metabolic regulation mechanism,and experimental models for basic research.The concept of"extremely flexible ureteroscopy"was proposed for the first time.Conclusion:Great achievements have been made for the prevention and treatment of kidney stones in the past five years,showing a promising future.In the future,surgical treatment of kidney stones is expected to achieve the goal of the highest stone removal rate,the lowest number of complications,the shortest rehabilitation time,and a comfortable and painless diagnosis and treatment process through the technique of"extremely flexible ureteroscopy".The research on the etiology of kidney stones may help to break through the bottleneck of the transformation of basic research findings for kidney stones from the aspects of the crystal structure of kidney stones,the repair mechanism of renal tubular epithelial cell damage,and the new experimental models for kidney stones.
万方数据
维普
