传染病信息2024,Vol.37Issue(3) :193-203.DOI:10.3969/j.issn.1007-8134.2024.03.001

抗新型冠状病毒小分子药物临床应用专家共识

Expert consensus on the clinical application of oral small-molecule antiviral drugs against COVID-19

中华医学会细菌感染与耐药防治分会 国家呼吸医学中心 国家呼吸系统疾病临床医学研究中心 钟南山 王贵强
传染病信息2024,Vol.37Issue(3) :193-203.DOI:10.3969/j.issn.1007-8134.2024.03.001

抗新型冠状病毒小分子药物临床应用专家共识

Expert consensus on the clinical application of oral small-molecule antiviral drugs against COVID-19

中华医学会细菌感染与耐药防治分会 国家呼吸医学中心 国家呼吸系统疾病临床医学研究中心 钟南山 1王贵强2
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作者信息

  • 1. 广州医科大学附属第一医院广州呼吸健康研究院国家呼吸系统疾病临床医学研究中心国家呼吸医学中心呼吸疾病全国重点实验室,广州 510120
  • 2. 北京大学第一医院感染疾病科,北京100034
  • 折叠

摘要

新型冠状病毒(新冠病毒)感染虽已不再构成"国际关注的突发公共卫生事件",但仍在全球范围内处于低水平流行.小分子口服药物是我国目前推荐的针对新冠病毒感染的主要抗病毒治疗方案.虽然国内已上市多种抗新冠病毒小分子药物,但目前尚无针对特殊人群的具体用药推荐.中华医学会细菌感染与耐药防治分会联合国家呼吸医学中心、国家呼吸系统疾病临床医学研究中心组织国内呼吸、病毒学、感染、重症、急诊、药学等各领域专家制订了本共识.本共识的主要内容包括7种抗新冠病毒小分子药物介绍,重点阐述了老年人群、合并慢性疾病人群、肿瘤患者、孕妇、儿童等14种特殊人群用药推荐,为临床医师规范用药提供建议.

Abstract

COVID-19 no longer constitutes a "public health emergency of international concern",which still has being spreading around the world at a low level. Small molecule drugs are the main antiviral treatment for novel coronavirus recommended in China. Although a variety of small-molecule antiviral drugs against COVID-19 have been listed in China,there is no specific drug recommendation for special populations. Society of Bacterial Infection and Resistance of Chinese Medical Association,together with the National Clinical Research Center for Respiratory Disease,and the National Center for Respiratory Medicine,organized domestic experts in various fields such as respiratory,virology,infection,critical care,emergency medicine and pharmacy to release Expert Consensus on the Clinical Application of Oral Small-Molecule Antiviral Drugs against COVID-19. The main content of this consensus includes the introduction of seven small-molecule antiviral drugs against COVID-19,focusing on the drug recommendations for 14 special groups such as the elderly,patients with complicated chronic diseases,tumor patients,pregnant women,and children,and providing suggestions for clinicians to standardize drug use.

关键词

冠状病毒感染/抗病毒治疗/小分子药物/早期/专家共识

Key words

coronavirus infections/antiviral therapy/small molecule drugs/early stage/expert consensus

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基金项目

广州实验室应急关键项目(EKPG21-06)

澳门科学发展基金(0022/2021/A1)

广东省特支计划科技创新青年拔尖人才项目(2021TQ060189)

国家中医药局交叉创新团队项目(ZYYCXTU-D-202201)

出版年

2024
传染病信息
解放军第三0二医院

传染病信息

CSTPCD
影响因子:1.366
ISSN:1007-8134
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