Objective To investigate the serum immunoglobulin (Ig)M,IgG,and neutralizing antibody levels and characteristics of recovered patients with SARS-CoV-2 infection and uninfected patients vaccinated against novel coronavirus (SARS-CoV-2). Methods The study were selected for medical workers in the third people' s hospital of kunming hospital from December 9,2022 to January 31,2023,including 36 recovered SARS-CoV-2 patients (recovery group) and 33 uninfected patients vaccinated against SARS-CoV-2 (vaccine group),and serum antibodies of the two groups were detected and analyzed. Results The IgM positivity rates in the rehabilitation and vaccine groups were 25.00％ and 18.19％,respectively,and the IgG and neutralizing antibody positivity rates were 100％,with no statistically significant differences in the positivity rates of the 2 groups (P>0.05). Both IgG and neutralizing antibody levels were higher in the rehabilitation group than in the vaccine group (P<0.05),However,the difference in IgM levels between the 2 groups was not statistically significant (P>0.05). The IgG levels were higher in women than in men in both groups (P<0.05),and neutralizing antibody levels were higher in men than in women (P<0.05). Conclusions IgG and neutralizing antibody levels were higher in the population recovering from the SARS-CoV-2 infection than in the vaccinated population. IgG levels were higher in women than in men in recovered SARS-CoV-2 infected and uninfected SARS-CoV-2 vaccinated patients,however,the level of neutralizing antibodies is higher in men than in women.
维普
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