[Background]Mycoplasma ovipneumoniae is a primary causative agent of respiratory illnesses in sheep and goats,leading to clinical manifestations such as coughing,wheezing,rhinorrhea,and wasting.The control of this pathogen poses a significant challenge due to its broad host range,prolonged duration of illness,obstacles in achieving successful in vitro cultivation,and variable antimicrobial sensitivity profiles.[Challenges]This complexity in managing Mycoplasma ovipneumoniae infections has led to considerable economic losses within the ovine sector.Current treatment strategies are hampered by these difficulties,highlighting the need for more effective control measures.[Strategies]Presently,immunization through vaccines is acknowledged as an efficient preventive strategy.However,the limited availability of commercial vaccines hampers their utility.Emerging studies advocate for the development of sheep breeds genetically resistant to Mycoplasma ovipneumoniae.Vaccination,while rapid and efficacious,fails to offer universal protection against all prevalent strains and is economically untenable,thus inhibiting the progress of the sheep industry in regions such as Xinjiang.[Conclusion]To ensure a sustainable solution and mitigate the financial burden,strategic breeding for intrinsic resistance to Mycoplasma ovipneumoniae infection in sheep populations presents a more practical and promising long-term approach to disease management.
NETL
NSTL
维普
万方数据
