Objective To explore the safety and effectiveness of percutaneous K-wire tibiotalocalcaneal temporary fixation for"damage control"of acute closed unstable ankle fractures.Methods A retrospective analysis was conducted on 23 patients with acute closed unstable ankle fractures treated with percutaneous K-wire tibiotalo-calcaneal temporary fixation between Jun.2018 and Mar.2022.This case series included 13 males and 10 females aged 18-78(mean 44.6)years,with 7 fall-related sprains,5 sports injuries,7 road traffic injuries and 4 falls from height.Tscherne classifications showed 8 cases of grade Ⅰ,8 grade Ⅱ and 7 grade Ⅲ.A manual reduction was performed under C-arm fluoroscopy;then a 2.5-mm and another 2.0-mm K-wire were percutaneously inserted longi-tudinally from distal to proximal across the tibiotalocalcaneal joint at the sole.The duration from the initial K-wire fixation to the second-stage internal fixation surgery was recorded,together with the incidence of related complica-tions and the Foot and Ankle Outcome Score(FAOS)at 12-month follow-up.Results None of the patients devel-oped complications such as skin necrosis,pin tract infection or poor wound healing.Patients waited for(9.5±2.5)days to receive internal fixation surgery,and the 12-month postoperative FAOS score was 85.8±4.6.Conclusion Percutaneous K-wire tibiotalocalcaneal temporary fixation in the management of acute closed unstable ankle joint fractures is cost-effective and safe,and we recommend it for emergent"damage control".