首页|单针法腰骶丛联合阻滞模拟战现场急救中对下肢创伤伤员的镇痛效果

单针法腰骶丛联合阻滞模拟战现场急救中对下肢创伤伤员的镇痛效果

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目的 评估单针法腰骶丛联合阻滞在跟随 120 救护车现场急救中对下肢创伤伤员镇痛的疗效,模拟其用于战现场的可行性及有效性,为提升战现场一线救治能力提供参考.方法 前瞻性选择 2023年 6 月—2023 年 11 月联勤保障部队第九六〇医院 120 急救中心现场收治模拟战时受伤的下肢创伤伤员 50例,男性 29 例,女性 21 例;年龄 20~60 岁,平均 45.7 岁;平均BMI(23.54±2.86)kg/m2;ASA分级:Ⅰ级 36例,Ⅱ级 14 例.采用随机数字表法分为观察组和对照组,各 25 例.到达创伤现场后,观察组于手持式便携超声引导下使用 0.25%盐酸罗哌卡因进行单针法腰骶丛联合阻滞,对照组肌肉注射盐酸吗啡 10 mg,操作均由同 1 名随行麻醉师完成.比较两组伤员镇痛即刻(T0)、转运途中 5 min(T1)、转运途中 15 min(T2)、入院即刻(T3)、入手术室时(T4)的镇痛效果、血流动力学水平.比较两组伤员的镇痛操作时间、镇痛起效时间、对镇痛效果的满意度评分及不良反应,比较两组伤员伤后 7 d、3 个月的创伤后应激障碍(PTSD)评分及慢性疼痛发生率.结果 T1、T2、T3、T4 时点,观察组静息疼痛数字评分(NRS)均低于对照组[(4.1±1.3)分 vs.(6.3±1.2)分、(2.7±1.2)分 vs.(5.0±0.9)分、(1.7±0.9)分 vs.(3.8±1.0)分、(1.2±0.7)分 vs.(2.9±0.8)分,P<0.05],观察组运动NRS均低于对照组[(5.4±1.6)分 vs.(7.8±1.2)分、(3.9±1.4)分 vs.(6.5±1.0)分、(2.8±1.1)分 vs.(5.4±1.1)分、(2.2±1.0)分 vs.(4.6±1.0)分,P<0.05];T1、T2、T3、T4 时点,观察组MAP[(99.4±7.6)mmHg、(95.4±6.1)mmHg、(94.2±6.2)mmHg、(94.6±5.4)mmHg]较对照组[(106.4±8.2)mmHg、(90.2±7.6)mmHg、(88.3±7.6)mmHg、(88.4±7.8)mmHg]更平稳,差异有统计学意义(P<0.05);相比对照组,观察组镇痛操作时间长、起效时间快[(6.1±0.8)min vs.(1.7±0.7)min,(5.9±1.0)min vs.(10.5±1.4)min],差异有统计学意义(P<0.05);两组HR、SpO2 在各时间点比较差异均无统计学意义(P>0.05);观察组患者对镇痛效果满意度评分高于对照组,差异有统计学意义(P<0.05);观察组不良反应发生率、补用吗啡镇痛比例、补用镇痛药物剂量[4%、24%、0(0,2.5)mg]低于对照组[52%、68%、5(0,10)mg],差异有统计学意义(P<0.05);观察组伤后 7 d、3 个月PTSD评分及慢性疼痛发生率[(12.10±3.58)分、(8.16±2.78)分、16%]均低于对照组[(28.20±8.07)分、(16.28±6.26)分、44%],差异有统计学意义(P<0.05).结论 单针法腰骶丛联合阻滞在模拟战现场急救情况下能够迅速且安全有效缓解下肢战创伤伤员疼痛,减少使用全身性止痛药物所带来的不良反应,降低PTSD及慢性疼痛发生率且伤员满意度更高.
Analgesic effect of single-acupuncture lumbosacral plexus block in simulated field emergency care for trauma patients with lower limb injuries
Objective To evaluate the analgesic effect of single-acupuncture lumbosacral plexus block during the 120-ambulance first aid on site for trauma patients with lower limb injuries,and to evaluate the feasibility and effectiveness in simulated battlefield.Methods From Jun.2023 to Nov.2023,the 120-ambulance center of No.960 Hospital of PLA Joint Logistics Support Force managed 50 cases of lower limb injuries on site,including 29 males and 21 females aged 20-60(mean 45.7)years.The average body mass index wasZ(23.54±2.86)kg/m2;the American Society of Anesthesiologists classification showed 36 cases of grade Ⅰ and 14 of grade Ⅱ.One anes-thetist was enrolled in the rescue team to stimulate battlefield emergency rescue and conduct all the analgesic treat-ments.Patients were divided into control group or observation group according to the random number table method,with 25 cases in each group.After arriving at the trauma scene,patients in the observation group received ultra-sound-guided(handheld)single-acupuncture lumbar plexus block with 0.25%ropivacaine,while those in the control group were intramuscularly injected with 10 mg morphine hydrochloride.The analgesic effect assessed by the numer-ical rating scale(NRS)and hemodynamic status were monitored at 5 time points:immediately after analgesia(T0),5 min during pre-hospital transportation(T1),15 min during pre-hospital transportation(T2),on admission(T3),and entrance of the operating room(T4).The operation time and onset time for analgesic treatment,adverse reac-tions,and satisfaction scores from patients were compared between the two groups,as well as the post-traumatic stress disorder scale-5th edition(PCL-5)scores at 7 d and 3 months after injury and the incidence of chronic pain.Results At T1,T2,T3,T4,the NRS at resting state was much lower in the observation group than in the control group(4.1±1.3 vs.6.3±1.2,2.7±1.2 vs.5.0±0.9,1.7±0.9 vs.3.8±1.0,1.2±0.7 vs.2.9±0.8,all P<0.05),moreover,the NRS at movement status was also much lower in the observation group(5.4±1.6 vs.7.8±1.2,3.9±1.4 vs.6.5±1.0,2.8±1.1 vs.5.4±1.1,2.2±1.0 vs.4.6±1.0,all P<0.05).At T1,T2,T3 and T4,the MAP(mmHg)was significantly more stable in the observation group(99.4±7.6,95.4±6.1,94.2±6.2,94.6±5.4)than that in the control group(106.4±8.2,90.2±7.6,88.3±7.6,88.4±7.8)(all P<0.05),while the heart rate and SpO2 showed no significant difference between the two groups(all P>0.05).The observation group re-vealed longer operation time for analgesia(min,6.1±0.8 vs.1.7±0.7)but much quicker relief of pain(min,5.9±1.0 vs.10.5±1.4)(both P<0.05).Much more patients in the observation group were satisfied with the analgesia effect(P<0.05).The incidence of adverse reactions(4%vs.52%),the proportion of patients with supplementary analgesia(24.0%vs.68.0%)and doses[mg,0(0,2.5)vs.5(0,10)]were much lower in the observation group(both P<0.05).The PCL-5 scores were also much lower in the observation group at 7 d(12.10±3.58 vs.28.20±8.07)and 3 months(8.16±2.78 vs.16.28±6.26),with less incidence of chronic pain(16.0%vs.44.0%,P<0.05).Conclusion Single acupuncture lumbosacral plexus block can rapidly,safely and effectively relieve the pain of trauma patients with lower limb injuries,with reduced side effects caused by the use of systemic analgesics,PTSD and chronic pain,and increased satisfaction.It is worthy of promotion and application in the early treatment of combat injuries.

Lower limb injuriesPain managementPrehospital disposal

贾云逸、高成杰、刘晓翔、唐文红

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山东第二医科大学麻醉学院,山东 潍坊 261021

联勤保障部队第九六〇医院麻醉科,济南 250031

下肢创伤 疼痛管理 院前处置

2024

创伤外科杂志
第三军医大学,大坪医院,野战外科研究所

创伤外科杂志

CSTPCD
影响因子:1.017
ISSN:1009-4237
年,卷(期):2024.26(12)