Clinical effect of laparoscopy combined with duodenoscopy on acute biliary pancreatitis complicated with common bile duct stone and the impact on postoperative recovery
Objective To investigate the clinical effect of laparoscopy combined with duodenoscopy on acute biliary pancreatitis(ABP)complicated with common bile duct stone.Methods A total of 149 patients with ABP and common bile duct stones who were admitted to Cangzhou People's Hospital from August 2020 to October 2023,including 68 males and 81 females,aged(60.85±10.39)years old,and the age range was 35～88 years old.According to the treatment plan,patients enrolled were divided into duodenoscopy group and choledochoscopy group.71 patients in the duodenoscopy group were treated with laparoscopy combined with duodenoscopy.78 patients in the choledochoscopy group were treated with laparoscopy combined with choledochoscopy.The surgical status,postoperative recovery,laboratory indicators,stress response indicators before and after surgery,and the occurrence of complications were compared between the two groups.Results Postoperative feeding recovery time and length of hospital stay were shorter in the duodenoscopy group as compared with the choledochoscopy group,and the difference was statistically significant(P＜0.05).On day 3 after surgery,the levels of PCT,hs-CRP and ALT in both groups were lower than preoperative levels.Meanwhile,the levels were lower in the duodenoscopy group,and the difference was statistically significant(P＜0.05).A week after surgery,serum superoxide dismutase(SOD)and glutathione peroxidase(GSH-Px)levels in both groups were lower than preoperative levels,and malondialdehyde(MDA)levels were higher than preoperative levels.Moreover,the levels of SOD and GSH-Px were higher,and MDA level was lower in the duodenoscopy group,and the difference was statistically significant(P＜0.05).There was no significant difference in the incidence of postoperative complications between the two groups(P＞0.05).Conclusion Compared to laparoscopy combined with choledochoscopy,laparoscopy combined with duodenoscopy is more conducive to the condition of patients with ABP and common bile duct stones.The latter can promote postoperative recovery without increasing the risk of postoperative complications.
Acute biliary pancreatitisCommon bile duct stoneLaparoscopyDuodenoscopyComplication
万方数据
维普
