摘要
维生素作为广泛参与人体生理功能的重要微量营养素,由于不能在体内合成或合成量不足,需要外源性补充,因此在肠外营养治疗中起重要作用.但目前对于肠外营养中维生素的使用剂量和监测,国内并无系统的指南或共识.为了进一步规范肠外营养中维生素的临床应用,中国营养学会医用食品与营养支持分会、中华医学会肠外肠内营养学分会(CSPEN)、上海市医学会肠外肠内营养学专科分会及上海市营养学会组织全国专家,在系统性文献检索的基础上,参考欧洲肠外肠内营养学会(ESPEN)、美国肠外肠内营养学会(ASPEN)、澳大利亚肠外肠内营养学会(AuSPEN)及CSPEN等相关指南共识,结合我国临床实践,经多次交流讨论,达成此共识.包括37条推荐意见,涉及成人肠外营养支持病人的脂溶性维生素(维生素A、D、E、K)和水溶性维生素(维生素C和维生素B1、B2、B6、B12、烟酸、泛酸、生物素和叶酸)的推荐剂量和监测.
Abstract
Vitamins,as important micronutrients widely involved in human physiological functions,play a significant role in parenteral nutrition therapy due to their inability to be synthesized or insufficient synthesis in the body,requiring exogenous supplementation. However,a consensus does not exist in China regarding the dosage and monitoring of vitamins in parenteral nutrition. Experts in the field are recruited by Chinese Nutrition Society for Medical Food and Nutrition Support,Chinese Society for Parenteral and Enteral Nutrition (CSPEN),Shanghai Medical Association for Parenteral and Enteral Nutrition and the Shanghai Nutrition Society to formulate a consensus paper.The current paper aims to provide standardized guidance for clinical use of vitamins in parenteral nutrition. The consensus paper is a composite of systematically reviewing pertinent literature,Chinese clinical practice and multiple sessions of debate,discussion,and composition,with reference to guidelines from European Society for Parenteral and Enteral Nutrition (ESPEN),American Society for Parenteral and Enteral Nutrition (ASPEN),Australasian Society for Parenteral and Enteral Nutrition (AuSPEN) and CSPEN.This includes 37 recommendations regarding the recommended dosage and monitoring of fat-soluble vitamins (vitamins A,D,E,K) and water-soluble vitamins (vitamin C and vitamins B1,B2,B6,B12,niacin,pantothenic acid,biotin,and folate) to serve varied adult parenteral nutrition patients.
维普
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