To solve the problem of low success rate in starting a certain type of low volume fraction gas engines, analysis and research was carried out. Based on the Fluent module of ANSYS Workbench, a three-dimensional mathematical model of the flow channel from the front of the fuel valve to the front of the turbocharger was established, and the model was calibrated. Based on this model, simulation calculations and optimization design were carried out, and validated on the low volume fraction gas engine. The experimental results show that the improved guided mixer can achieve an excess air coefficient of over 0.7 before the inlet of the turbocharger when the gas volume fraction is 11%-14%, thus the success rate of start-up was greatly improved.