Standard Test Guidelines for Skin Safety and Efficacy Testing of Cosmetics
Cosmetics are a major part of modern life,and consumer demand for better cosmetics continues to increase with the development of society.Using life science research methods,including toxicology,safety testing can eliminate the risks of adverse reactions to skin and other tissues caused by cosmetics.Efficacy testing helps to elucidate the mechanisms of various active ingredients in cosmetics on the skin,strengthen scientific supervision in the industry,and prevent false advertising.Therefore,regulating cosmetics'safety and efficacy is essential for the safety of the users and the healthy development of the consumer market.This article briefly summarizes the standard documents regarding cosmetics in the European Union and China.The safety testing includes phototoxici-ty,skin irritation,skin corrosion,and skin sensitization,while the efficacy testing includes antioxidant,anti-aging and anti-wrinkle,moisturizing,and whitening.This paper also summarizes commonly used cosmetic safety models,explores the development trends of cosmetic safety,and discusses efficacy testing methods.Additionally,this paper aims to provide reference for basic research in dermatology and toxicology,provide ideas for exploring new effica-cy and mechanisms of more active ingredients,promote the research and application of alternative methods,and provide a basis for establishing more promising research methods.
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