Anesthesia Effect and Safety Analysis of Cyclopol in Endovascular Repair of Type B Aortic Dissection
Objective: To observe the anesthetic effect and safety of cyclopol in endovascular repair of type B aortic dissection. Meth-ods: A total of 107 patients with type B Aortic dissection treated by endovascular repair were selected as the study subjects. The enrolled patients were divided into observation group (54 cases) and control group (53 cases) by random number table method. The control group was given routine intravenous anesthesia with propofol, and the observation group was given intravenous anesthesia with ciprofol. The an-esthesia effect and safety of two groups of patients were compared. Results: The HR and MAP of the two groups before surgery (T0) were similar (P>0.05); Under different anesthesia schemes, the HR and MAP of the observation group and 5 minutes after induction (T1), which were higher than those of the control group; After induction for 10 minutes (T2), the HR, MAP. Compared with the control group, the above indicators were all higher (P<0.05); The HR and MAP of the observation group during Tracheal intubation(T3) and, which were similar to those of the control group (P>0.05); At the end of the surgery(T4), the HR, MAP. Compared with the control group, the above indicators were all higher (P<0.05). The postoperative recovery time of the observation group, PACU retention time, postoper-ative RASS score, and the number of sedation relief cases, which was similar to the control group (P>0.05). The cognitive function of the two groups of patients at T0 was similar (P>0.05); Under different anesthesia regimens, the MMSE score and MoCA score of the ob-servation group after awakening, respectively. Compared with the control group, the above indicators were all higher (P<0.05). The inci-dence of anesthesia related adverse reactions in the observation group was 11.11％ , which was lower compared to the control group of 28.30％ (P<0.05). Conclusion: Cyclopol can effectively maintain the stability of perioperative signs in patients with type B Aortic dissec-tion undergoing endovascular repair. Its anesthetic and sedative effects are equivalent to those of propofol, but it can better protect the pa-tient's neurological function and reduce the risk of anesthesia related adverse reactions.
type B aortic dissectionendovascular repair surgerygeneral anesthesiacyclopol
万方数据
维普
