Effect of Phacoemulsification and Femtosecond Laser Assisted Surgery on Tear Film Rupture Time in Cataract Patients
Objective: To analyze the effect of phacoemulsification and femtosecond laser assisted surgery on tear film rupture time of patients with cataract, in order to provide reference for clinical treatment of cataract. Methods: A total of 100 cataract patients diagnosed were divided into control group (50 cases, 50 eyes) and observation group (50 cases, 50 eyes) by random number table method. The control group underwent phacoemulsification surgery, and the observation group underwent femtosecond laser assisted phacoemulsification surgery. Surgical indicators, tear film rupture time, proportion of corneal endothelial cells and hexagonal cells, and levels of tear inflammatory factors [transforming growth factor-β1 (TGF-β1), interleukin-6 (IL-6), interleukin-8 (IL-8), tumor necrosis factor-α (TNF-α)] before and 2 months after surgery were compared between the two groups. Results: The intraoperative ultrasound energy in the observation group was lower than that in the control group, and the ultrasound time was shorter than that in the control group. The rupture time of tear film in both groups was longer 1 month after surgery than before surgery, and the observation group was longer than that in control group. The proportion of corneal endothelial cells and hexagonal cells was lower 1 month after surgery than before surgery. However, the proportion of corneal endothelial cells and six-shaped cells in observation group was higher than that in control group. The levels of TGF-β1, IL-6, IL-8 and TNF-α in 2 groups increased 2 months after surgery compared with those before surgery, but the observation group was lower than the control group, and the differences were statistically significant (P<0.05). Conclusion: Femtosecond laser assisted phacoemulsification in cataract patients can reduce the ultrasonic energy, prolong the rupture time of tear film, and reduce the loss of corneal endothelial cells and the level of tear inflammation.
ultrasonic emulsificationfemtosecond lasertear film rupture timecorneal endothelial cell
万方数据
维普
