Clinical Features and Resistance Analysis of Streptococcus Anginosus Group Infection from 2020 to 2021 in Changzhi Area
Objective:To analyze the clinical features and drug resistance of Streptococcus anginosus group(SAG)infection from 2020 to 2021 in Changzhi area.Methods:Data from 189 patients with SAG infection were collected for clinical feature analy-sis.WHONET5.6 software was used to analyze the types of SAG strains and the results of drug sensitivity.It was also used to com-pare the drug resistance rates of strains from different sites of infection.Results:The number of SAG-positive cases was higher in males(61.90%)than females(38.10%)in Changzhi area,and the mean age was(51.0±14.5)years.There were 117 patients(61.90%)with abscess formation,and Streptococcus intermadius has the highest probability of forming abscesses.The types of in-fections caused by SAG were mainly oral infections(25.93%,49 cases)and intra-abdominal infections(19.05%,36 cases).The proportion of patients with underlying diseases,the proportion of immunosuppressed diseases,the length of stay and the values of in-flammatory indexes(C-reactive protein,serum amyloid A,procalcitonin)in the SAG bloodstream infection group were higher than those in the non-bloodstream infection group(P<0.05).The resistance rates of SAG to clindamycin,erythromycin,tetracycline and levofloxacin were 73.04%,65.14%,38.62%and 9.00%,respectively.There was a significant difference in the resistance rate of SAG isolates to levofloxacin in the oral,abdominal and genitourinary sites(P<0.05),and it was found that the resistance rate of SAG isolates at the genitourinary infection sites was significantly higher than that of isolates at oral and abdominal infection sites(P<0.05).Conclusions:If patients with SAG infection had underlying diseases,immunosuppression,and significantly in-creased inflammatory index values,attention should be paid to whether patients had SAG bloodstream infections.The SAG had a high resistance rate to macrolides and lincosamides.
NETL
NSTL
万方数据
维普
