The Chain Mediating Effect of Disease Perception and Depression on the Activity of Daily Living and Health-related Quality of Life in Patients with Proliferative Diabetic Retinopathy
Objective:To investigate the chain mediating effects of disease perception and depression on activities of daily liv-ing and health-related quality of life in proliferative diabetic retinopathy.Methods:356 patients with proliferative diabetic retinopa-thy were measured by activities of daily living questionnaire,simple disease perception questionnaire,self-rating depression Scale,and quality of life scale for patients with visual impairment of eye disease.The chain mediation effect was tested using the Process software Bootstrap method.Results:Activities of daily living were negatively correlated with disease perception and depression(r=0.336,P＜0.01;r=0.260,P＜0.01),and positively correlated with health-related quality of life(r=-0.365,P＜0.01);The per-ception of illness was positively correlated with depression(r=0.308,P＜0.01)and negatively correlated with health-related quality of life(r=-0.888,P＜0.01).Depression was negatively correlated with health-related quality of life(r=-0.391,P＜0.01).Dis-ease perception and depression had a significant chain mediating effect between activities of daily living and health-related quality of life(P＜0.05),the mediating effect was-0.25,and the mediating effect accounted for 83.33％.Conclusion:Activities of daily liv-ing are an important factor affecting health-related quality of life in proliferative diabetic retinopathy,and disease perception and de-pression play a chain mediating role.
diabetic retinopathyactivities of daily livingquality of lifedisease perceptiondepression
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