微波消融治疗孤立性甲状腺微小乳头状癌疗效观察
Effect of Micro wave Ablation for the Treatment Of Unifocal Papillary Thyroid Microcarcinoma
周玉叶 1吕玲 1吕顺 1巨雅莉 1马鹏杰 1牛惠萍2
作者信息
- 1. 长治医学院(山西长治 046000)
- 2. 长治医学院附属和平医院超声医学科
- 折叠
摘要
目的:探讨孤立性甲状腺微小乳头状癌微波消融的治疗效果.方法:回顾性分析72例采用微波消融治疗的甲状腺微小乳头状癌患者,在术后即刻超声造影评估消融范围并计算坏死灶的体积,于术后1、3、6、12个月行常规超声检查,观察病灶吸收情况,比较病灶的体积、体积缩小率、甲状腺功能,根据结节最大直径分为直径＞5 mm和直径≤5 mm,比较病灶的体积缩小率,观察有无新发病灶及淋巴结转移.结果:术后1、3、6、12个月随访,体积缩小率分别为37.3％、73.5％、91.5％、100.0％,差异有统计学意义(P＜0.05);最大直径＞5 mm的结节体积缩小率小于结节最大直径≤5 mm组,差异有统计学意义(P＜0.05);术后1个月与术前甲状腺功能变化差异无统计学意义(P＞0.05),随访1年未发现新发病灶及颈部淋巴结转移.结论:微波消融治疗孤立性甲状腺微小乳头状癌疗效确切,并且体积越小吸收越快.
Abstract
Objective:To investigate the therapeutic effect of microwave ablation of solitary micropapillary thyroid carcinoma.Methods:A retrospective analysis was performed in 72 patients with micropapillary carcinoma of the thyroid treated by microwave ablation.The ablation range and volume of necrotic lesion were evaluated by contrast-enhanced ultrasound immediately after sur-gery.Routine ultrasound examination was performed at 1,3,6 and 12 months after operation to observe the absorption of the le-sions,and compare the volume,volume reduction rate and thyroid function of the lesions.According to the maximum diameter of nodules,the nodules were divided into diameter＞5 mm and diameter ≤5 mm.The volume reduction rate of lesions was com-pared to observe whether there were new lesions and lymph node metastasis.Results:At 1,3,6 and 12 months follow-up,the volume reduction rates were 37.3％,73.5％,91.5％and 100.0％,respectively,with statistical significance(P＜0.05).The size reduction rate of nodules with maximum diameter＞5 mm was lower than that of nodules with maximum diameter ≤5 mm,and the difference was statistically significant(P＜0.05).There was no statistically significant change in thyroid function between 1 month after surgery and before surgery(P＞0.05),and no new lesions or cervical lymph node metastases were found at 1-year follow-up.Conclusion:Microwave ablation is effective in the treatment of solitary micropapillary thyroid carcinoma,and the smal-ler the size,the faster the absorption.
关键词
甲状腺乳头状癌/微波消融/超声介入Key words
papillary thyroid cancer/microwave ablation/ultrasound intervention引用本文复制引用
出版年
2024
NETL
NSTL
万方数据