首页|基于古今医案云平台的叶天士治疗郁证合并不寐的用药规律分析

基于古今医案云平台的叶天士治疗郁证合并不寐的用药规律分析

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目的:基于"古今医案云平台(V2.3.5)",分析叶天士治疗郁证与不寐的处方用药规律及特点.方法:对《临证指南医案·不寐》与《临证指南医案·郁》记载的处方药物进行规范化处理后,分别导入古今医案云平台建立叶天士不寐篇与郁证篇的数据库.采用统计分析、关联分析对导入中药的四气、五味、归经、功效、使用频次、常用药物组合进行分析.结果:《临证指南医案》卷六郁证篇纳入总案例40篇,涉及83味中药;《临证指南医案》卷六不寐篇纳入总案例15篇,涉及单味中药数44味.叶氏治疗郁证与不寐使用中药的药性均以平、温、寒为主,药味均以苦、甘、辛为主,主归肺、心、脾经.茯苓、牡丹皮、郁金、当归、陈皮为叶氏治疗郁证使用频次最高的前5味药;不寐篇高频药物前6味依次为茯苓、酸枣仁、知母、半夏、炙甘草、川芎.不寐篇关联分析得出知母-酸枣仁,酸枣仁-知母,酸枣仁-炙甘草三个组合;不寐篇关联分析得出生姜-茯苓,栀子-牡丹皮,香附-茯苓;将郁证使用频率较高的药对进行组合,可得丹栀逍遥散加减,将不寐高频药对进行组合可得酸枣仁汤.结论:叶天士治疗郁证与不寐时使用单味药的药性、药味、归经、功效有很大的共性,高频药对组合得到的新处方均可治疗郁证与不寐.表明郁证与不寐在治疗上具有深刻的内在联系.
Analysis of the Medication Pattern of Ye Tianshi's Treatment of Depression Combined with Insomnia Based on the Cloud Platform of Ancient and Modern Medical Cases
Objective:To analyze the prescription rules and characteristics of Ye Tianshi in the treatment of depression syn-drome and insomnia based on the cloud platform of ancient and modern medical records.Methods:After standardized treatment of the prescription drugs recorded in"Clinical Guide Medical Records·Insomnia"and"Clinical Guide Medical Records·Yu",which were imported to the cloud platform of ancient and modern medical records to establish the database of Ye Tianshi's insomnia and depression.The statistical analysis and correlation analysis were used to analyze the four gases,five tastes,classics,efficacy,fre-quency of use and common drug combinations of imported Chinese medicines.Results:The first 6 tastes of high frequency drugs were Poria,jujube kernel,Zhi mother,pinellia,scorched licorice,Chuanxiong.The correlation analysis of the Bumei chapter ob-tained three combinations of fructuum-sour jujube kernel,sour jujube kernel,sour jujube kernel and grilled glycyrrhiza.The corre-lation analysis of the Yuzheng chapter showed that ginger-Poria,gardenia-Moutan bark,fragrant-poria.The combination of drugs with higher frequency of depression syndrome can be added or reduced by Danzhi Xiaoyao powder.Suanzao Ren decoction can be obtained by combining the sleepless high frequency medicine pair.Conclusion:The properties,tastes,meridians and effects of sin-gle medicine used by Ye Tianshi in the treatment of depression and sleeplessness have great commonality.It shows that depression syndrome and insomnia have profound internal relations in the treatment.

sleeplessstagnant emotional conditionancient and modern medical case cloud platforma guide to clinical evidence

曾宪馨、梁芬兰、聂鹏兵、张永全

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广西中医药大学附属瑞康医院(广西南宁 530200)

不寐 郁证 古今医案云平台 《临证指南医案》

2024

长治医学院学报
长治医学院

长治医学院学报

影响因子:0.609
ISSN:1006-0588
年,卷(期):2024.38(4)
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