Effect of SPI Combined with CSI Monitoring on the Amount of Remifentanil Used in Elderly Patients Undergoing Laparoscopic Cholecystectomy
Objective:To observe the feasibility of surgical pleth index(SPI)combined with cerebral state index(CSI)in guiding the dosage of opioids during laparoscopic cholecystectomy in elderly patients.Methods:A total of 40 patients with laparo-scopic cholecystectomy(age≥65 years old,ASA grade Ⅱ~Ⅲ)were selected.Two groups was divided into by the random number table method,which were SPI+CSI monitoring(group S)and conventional anesthesia management group(group C),with 20 pa-tients in each group.The consumption and duration of remifentanil,the additional amount of postoperative analgesics,and the QoR-15 scores of patients 24 h before and after surgery.Results:The dosage of remifentanil in group S was 0.083 μg·kg-1·min-1,which was lower than that in group C by 0.109 μg·kg-1·min-1,and the difference was statistically significant(P<0.05).The postoperative analgesic drug usage rate in group S was 15%lower than 45%in group C,and the difference was statistically signifi-cant(P<0.05).There was no significant difference in the QoR-15 score between the two groups before surgery(P>0.05),and the QoR-15 score in group S was higher than in group C after surgery(P<0.05).Conclusion:In elderly patients undergoing endo-scopic cholecystectomy,SPI combined with CSI guided administration can significantly reduce the use of intraoperative opioids,re-duce the addition of postoperative analgesics and promote the early recovery quality of patients.