摘要
目的:探讨灰阶超声联合正电子发射断层显像/计算机体层成像(PET/CT)对肺癌颈部淋巴结转移的临床诊断价值.方法:回顾性分析 499 例疑似肺癌颈部淋巴结转移患者的影像学检查资料,与病理学检查结果对照,构建受试者工作特征(ROC)曲线,分析比较灰阶超声、PET/CT及两者联合的诊断效能.结果:灰阶超声、PET/CT对肺癌颈部淋巴结转移的敏感度、特异度、阳性预测值、阴性预测值、准确度分别为 84.25%、65.25%、88.67%、56.20%、79.75%和 76.37%、71.18%、89.53%、48.27%、75.15%,灰阶超声联合 PET-CT 的敏感度、特异度、阳性预测值、阴性预测值、准确度分别为 87.13%、59.32%、87.36%、58.82%、80.56%,两者联合诊断效率最高,差异具有统计学意义(P<0.05).结论:灰阶超声联合PET/CT能提高对肺癌颈部淋巴结转移诊断的准确率,具有重要的临床应用价值.
Abstract
Objective:To investigate the clinical diagnostic value of grayscale ultrasound combined with positron emission tomography/computed tomography in the cervical lymph node metastasis of lung cancer.Methods:The imaging data of 499 patients with cervical lymph node metastasis with suspected lung cancer were retrospectively analyzed,and the receiver operating characteris-tic(ROC)curve was constructed to analyze and compare the clinical diagnostic value of grayscale ultrasound,PET/CT and grayscale ultrasound combined with PET/CT.Results:The sensitivity,specificity,positive predictive value,negative predictive val-ue,and accuracy of grayscale ultrasound for cervical lymph node metastasis in lung cancer were 84.3%,65.3%,88.7%,56.2%,and 79.8%,respectively.The sensitivity,specificity,positive predictive value,negative predictive value,and accuracy of PET/CT for cervical lymph node metastasis in lung cancer were 76.4%,71.2%,89.5%,48.3%,and 75.2%,respectively.The sensitivi-ty,specificity,positive predictive value,negative predictive value,and accuracy of grayscale ultrasound combined with PET/CT were 87.1%,59.3%,87.3%,58.8%,and 80.6%,respectively.The combined diagnostic efficiency was the highest,and the difference was statistically significant(P<0.05).Conclusion:Grayscale ultrasound combined with PET/CT can improve the accu-racy of diagnosis of cervical lymph node metastasis in lung cancer,which has important clinical application values.
维普
万方数据