Effects of different enteral nutrition interventions on intestinal and anal function in patients undergoing preventive colostomy of rectal cancer resection
Objective To investigate the effects of different enteral nutrition interventions on intestinal and anal function in patients undergoing preventive colostomy of rectal cancer resection (Dixon).Methods Sixty patients undergoing Dixon preventive colostomy in our hospital were randomly assigned into two group,intact protein-based postoperative early enteral nutrition (EN) group (Fresubin group) and intact protein-based postoperative early EN that contained dietary fiber group (Nutrison Fibre group).There were 30 patients in each.Both groups were given enteral nutrition support for 1 week.The changes of serum albumin(ALB),pre-albumin (PAB),transferrin(TF) and other nutrition indexes in both groups were recorded before and after the operation.Changes of gastrin,initial anal exhaust time after preventive colostomy and other anorectal function indices were compared between the two groups.The safety and feasibility of early enteral nutrition were analyzed.Results In Nutrison Fibre group,ALB and PAB increased significantly on the 4th day after the operation compared with 1 day before the operation and were significantly higher than that in the Fresubin group (P ＜ 0.05).On the 8th day after operation,gastrin level [(105.48±10.73) pg/mL] in Nutrison Fibre group was significantly higher than that in Fresubin group (P ＜ 0.05).The initial anal exhaust time after preventive colostomy in Nutrison Fibre group [(4.37±0.56) d] was significantly shorter than Fresubin group (P ＜ 0.05).There was no significant difference in adverse reactions between the two groups(P ＞ 0.05).There were a significant correlation of ALB,PAB and TF with initial anal exhaust time after preventive colostomy (P ＜ 0.05).Conclusion Compared with Fresubin,nutrison Fibre dietary fiber enteral nutrition can significantly improve ALB,PAB,TF and other nutrition indices in patients undergoing Dixon preventive colostomy.It can also promote anorectal function recovery,with favorable safety profile.
Rectal cancerDietary fiberEnteral nutritionColostomyAnorectal function
国家科技期刊平台
NSTL
万方数据
维普
