结直肠肛门外科2024,Vol.30Issue(1) :28-34.DOI:10.19668/j.cnki.issn1674-0491.2024.01.006

肠道微生物群与结直肠癌发生发展的关系

Relationship with intestinal microbiota and the occurrence and development of colorectal cancer

张妍生 高峰 马秀芬
结直肠肛门外科2024,Vol.30Issue(1) :28-34.DOI:10.19668/j.cnki.issn1674-0491.2024.01.006

肠道微生物群与结直肠癌发生发展的关系

Relationship with intestinal microbiota and the occurrence and development of colorectal cancer

张妍生 1高峰 2马秀芬1
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作者信息

  • 1. 甘肃省妇幼保健院乳腺一科 甘肃兰州 730050
  • 2. 中国人民解放军联勤保障部队第九四○医院结直肠肛门外科 甘肃兰州 730050
  • 折叠

摘要

结直肠癌是最常见的恶性肿瘤之一,其发生发展与机体的内外环境有关.动态平衡的肠道微生物群在参与营养物质消化吸收、维持新陈代谢、调节免疫功能等方面发挥着重要作用,但如果肠道微生物群发生失调,则会对机体造成多方面的严重危害.本文对肠道微生物群的结构、功能、微生物群失调对肠道结构功能的损害及其与结直肠癌发生发展的关系进行综述,以期对结直肠癌的综合防治提供参考.

Abstract

Colorectal cancer is one of the most common malignancies,and its occurrence and development are related to the internal and external environment of the body.The dynamically balanced intestinal microbiota plays an important role in participating in the digestion and absorption of nutrients,maintaining metabolism,and regulating immune func-tion.However,if the intestinal microbiota is imbalanced,it can cause various serious harm to the body.This article re-views the structure and function of the intestinal microbiota,the damage caused by microbial imbalance to the intestinal structure and function,and its relationship with the occurrence and development of colorectal cancer,aiming to provide references for the comprehensive prevention and treatment of colorectal cancer.

关键词

结直肠癌/肠道微生物群/致癌机制

Key words

colorectal cancer/intestinal microbiota/carcinogenesis mechanism

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出版年

2024
结直肠肛门外科
广西医科大学

结直肠肛门外科

CSTPCD
影响因子:0.957
ISSN:1674-0491
参考文献量52
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