In order to increase the drainage area of development wells and increase the output of single wells,the proportion of large displacement wells and horizontal wells in development wells is gradually increasing.The change of borehole trajectory leads to the increase of friction and torque during drilling,and the problems of holding in torque and sticking frequently occur during tripping.Therefore,GLUBE,an efficient lubricant that can meet the product standards of CNPC lubricants and whose lubrication performance indexes are better than conventional lubricants,was obtained through molecular design,synthesis and comparative evaluation of performance.According to the results of system evaluation,the recommended addition of lubricant is 2%,the temperature resistance can reach 180℃,and the salt resistance is 20%.When the cuttings content is high at the end of the drilling operation,the lubricant addition can be increased to 3%.The field application results showed that GLUBE could reduce torque by 25.49%at 2%addition.In the high-risk stuck well section,no stuck phenomenon occurred after the cable was stationary for 20 min,which could reduce the risk of sticking of the test instrument and ensure the safe and rapid follow-up electrical measurement operation,and had a good prospect of popularization and application.