Synthesis of Ethylamine Ditellurium Ether and Studies on Enzymatic Properties of GPx
As a very important antioxidant enzyme in the human body,glutathione peroxidase(GPx)plays a very important role in the removal of excess peroxide produced by physiological reactions.Due to the low catalytic activity of artificial intelligence GPx enzyme,this paper designed and synthesized ethylamine ditellurium ether molecules containing GPx active center tellurium and two primary amino groups.When pH=7,the activity was 1.6±0.02μmol·min-1·μmol-1,which was 3 orders of magnitude higher than that of classical small molecule GPx artificial enzyme.
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