Research Progress in Fermentation Technology of Bacillus Subtilis
Various fermentation engineering strategies involved in the fermentation process of Bacillus subtilis were systematically reviewed.The selection of high-yield strains,optimization of culture media,setting of fermentation conditions,and precise control of the fermentation process were discussed.Methods to enhance strain productivity through traditional breeding techniques and modern genetic engineering approaches were explored.The effects of different nutrients and additives on bacterial growth and product formation were analyzed.The impact of factors such as temperature,pH,and dissolved oxygen on the fermentation process and their optimization strategies were introduced.Additionally,dynamic monitoring and control methods of the fermentation process to achieve efficient production were also discussed.The latest research status in the field of Bacillus subtilis engineering bacteria fermentation was comprehensively introduced,the current research results and existing problems were summarized,and the future research direction and possible development trend were put forward.
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