首页|Corticosteroids Treatment of Patients with Coronavirus Disease 2019:A Propensity Score Matching Study
Corticosteroids Treatment of Patients with Coronavirus Disease 2019:A Propensity Score Matching Study
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The role of corticosteroids in the treatment of coronavirus disease 2019(COVID-19)is controversial.In the present study,we evaluated the effects of adjuvant corticosteroids treatment on the outcome of patients with COVID-19(n=966),using Propensity Score Matching to adjust for potential differences between the corticosteroids group(n=289)and the non-corticosteroids group(n=677).Analysis of data without adjusting differences in baseline characteristics indicated that the proportion of mechanical ventilation and the mortality was higher in the corticosteroids treatment group in total or severe/critical patients.The duration of viral shedding was longer in the non-corticosteroids treatment group in total or general/mild patients.After adjusting the difference between the corticosteroids and non-corticosteroids treatment group,the analysis revealed that the use of corticosteroids had no effect on the duration of viral shedding,in-hospital mortality or 28-day mortality.
severe acute respiratory syndrome coronavirus 2coronavirus disease 2019corticosteroidsmortalityviral shedding
Department of Respiratory and Critical Care Medicine,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China
This work was supported by the HUST COVID-19 Rapid Response Call
NETL
NSTL
万方数据
维普
