首页|Trends in Coronavirus Disease 2019 Hospitalization and Prognosis: Gender Effect

Trends in Coronavirus Disease 2019 Hospitalization and Prognosis: Gender Effect

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We here aimed to investigate the impact of gender on the clinical characteristics and laboratory results of patients with coronavirus disease 2019 (COVID-19) and provide clues to the pathological mechanisms underlying COVID-19.A retrospective study was performed.Clinical characteristics,severity of lung infection,laboratory results,and prognoses of patients of different gender were analyzed.A total of 242 patients were finally included.The median age was 58 years (IQR: 40-68),including 54 (22.3％) hospital staffs.Ninety-four (38.8％) were male and 148 (61.1％) were female.The proportion of patients with diabetes was significantly higher in the male group than in the female group (P=0.034).Male patients had a significantly larger proportion of severe lung infection,higher leukocyte count,neutrophil count,neutrophil-to-lymphocyte ratio,C-reactive protein,and procalcitonin than female.Furthermore,male patients had worse liver,cardiac,and coagulation function than their female counterparts.Male patients with COVID-19 showed more severe inflammation reaction and coagulation dysfunction than female patients.In conclusion,gender is associated with host response to SARS-CoV-2 infection.

COVID-19genderblood routinecoagulation functioninflammation

Mei-jing SHI、Jia-gao LV、Li LIN、Jun-yi GUO

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Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

Department of Emergence, General Hospital of the Yangtze River Shipping, Wuhan 430030, China

This work was supported by the National Natural Science Foundation of ChinaThis work was supported by the National Natural Science Foundation of ChinaHubei Province Health and Family Planning Scientific Research ProjectNatural Science Foundation of Hubei ProvinceFundamental Research Fund for the Central Universities (HUST)Science and Technology Project Foundation of WuhanOutstanding Young Investigator Foundation of Tongji Hospital

8157041681570337WJ2019M1202019CFB6682017KFYXJJ0992017060201010175YXQN009

2021

10.1007/s11596-021-2348-8

当代医学科学(英文)
同济医科大学

当代医学科学(英文)

SCI
ISSN：2096-5230
年,卷(期)：2021.41(2)
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