It is a fundamental work to accurately evaluate the pattern and spatial disparity of regional economic development in order to promote coordinated economic development. Spatial filed is an abstract concept to de- fine the potential difference came from the process o f the growth pole of regional economy driving the eco- nomic development of periphery areas through transport corridors. According to the "pole-axis" system theory, regional interaction theory and energy space theory, the article characterizes the spatial field with the applica- tion of nodality index and regional accessibility. With the application of spatial field, it analyzes the spatio-tem- poral characteristics of macro-economic disparities, the three zones and the economic disparities in the North- ern-Southern China from inter-province, inter-city, inter-county. Moreover, the article reveals the interaction mechanism of spatial variation of regional economic development, and identifies the spatial type based on the pattern of regional development in China. The results indicates that the imbalance of China' s regional econo- my has expanded from 2000, while the economic disparities are different at different research scales. Secondly, the internal economic disparities of the three zones showed a significant feature with "anti-natural gradient"; the differences between the Southern and Northern China evolves from "South and North are in balance" to "South is stronger than North". Moreover, the internal economic disparities of both North and South presented a tendency to expand. Thirdly, China' s regional economic growth showed a significant spatial polarization. The local accumulation model of economic growth is differentiation and regularity. Fourthly, spatial pattern of the level of regional economic development in China could be divided into 5 zones and 23 sub-units, and dif- ferent types of areas should implement a targeted development strategy in the future.