To understand the interaction between sampling machines and lunar soil simulant,and to verify the feasibility of modular modeling of lunar soil sampling machines.The experimental study on mechanical penetration load under different conditions was carried out,based on the CUG-1A lunar soil simulant developed by China University of Geosciences(Wuhan),and the theoretical model was established based on the experimental results for verification.The average growth rate of penetration resistance of each machine in the shallow simulation of lunar soil was 19.9%,which was increased to 38.18%in the shallow simulation,and 63.43%in the deep simulation.The average error of penetration velocity to penetration resistance was 2.5%;the average growth rate between penetration angle and penetration resistance was 62.85%;the penetration resistance of different cross-section machines was approximately 1∶2∶3∶4.At the same time,the modular verification of the machine structure was carried out,and the accuracy of the test and model can reach more than 85%.The penetration resistance of sampling machines is significantly correlated with penetration depth,mode and machine structure,and the modular theoretical model can be established to accurately predict the penetration resistance of machines under different conditions.