Survival analysis of 155 esophageal squamous carcinoma patients with metastastic lymph nodes (T1～44NIM0)
AIM: To investigate the effect of tumor invasive depth and number of melastatic lymph nodes on the prognosis of patients with stage N1 thoracic esophageal squamous cell carcinoma and to explore the pathological mechanism of different prognosis and proper postoperative adjuvant therapy. METHODS: Clin-icopathological and follow-up data of 155 patients, who had undergone simple resection of thoracic esophageal squamous cell carcinoma, were studied using Kaplan-Meier survival curves and Cox-model analysis. RESULTS: Among all the 155 cases, 2 were staged to T1 N1, 46 to T2N1, 103 to T3N1, and 4 to T4N1. The 1, 3 and 5-year survival rates of patients who had less than 4 metastatic lymph nodes were significantly higher than those who had more than 4 (P<0. 05). But, no obvious statistical significance was found in sex, age, tumor site or cellular differentiation. CONCLUSION: The number of metastatic lymph nodes is a vital factor influencing the prognosis and survival of patients with thoracic esophageal squamous cell carcinoma. However, multi-center randomized control test is needed to prove the benefit of postoperative treatment and extended lymph node dissection.
NETL
NSTL
万方数据
