Randomized control clinical trial in multi-organ dysfunction by bee sting
AIM: To analyze and compare the effect of conventional therapy, hemoperfusion or hemoperfusion combined with continuous renal replacement therapy (CRRT) to treat multi-organ dysfunction by bee sting. METHODS: Twenty-four patients with bee sting-caused multi-organ dysfunction were studied. The 8 patients who refused hemoperfusion or CRRT were put in conventional therapy group, and the other 16 patients were put to HP group or HP + CRRT group by random digits table ( n = 8, respectively). Renal function, hepatic function, CRP, creatine kinase and MB isoenzyme of creatine kinase were detected before and after treatment, and the recovery rate, the average hospital days and fatality rate were compared. RESULTS: Two cases died in conventional group, with the fatality rate 25. 0% (2/8) , recovery rate 62.5% (5/8) and the average hospital days (17.8 ±2.3)d. The average hospital days were respectively (10. 6 ± 1.9 ) d and (8.3±1.2)d in HP group and in HP + CRRT. Recovery rate in HP and HP combined with CRRT was 87.5% and 100.0% , respectively. CONCLUSION: HP combined with CRRT is the most effective in treating multi-organ dysfunction by bee sting a-mong the three therapeutic methods under study. HP combined with CRRT better improves renal function, hepatic function, creatine kinase and MB isoenzyme of creatine kinase, and shortens the hospital days.
bites and stingswasp venomsmultiple organ failurehemoperfusionrenal replacement therapy
NETL
NSTL
万方数据
维普
