Recrudescent soft tissue sarcoma treated by 12C6+ heavy ion beam radiotherapy
AIM: To report the treatment of recrudescent soft tissue sarcomas by China-made heavy ion accelerator of the 12C6+ heavy ion beam and to evaluate the pros and cons of high-ami low-LET radiotherapy in the clinical application. METHODS: Three patients pathologically diagnosed as having soft tissue sarcoma, two in the abdomen and one in the back, voluntarily took heavy ion beam radiotherapy. All 3 cases were recurrent patients, who had had surgical and radiotherapy treatment but no good results. Each of the patients was exposed to 80-100mev/u heavy ion beam, a total dose of 72-120GYE/6-12f (RBE = 3). RESULTS: Three months after the treatment, tumors disappeared in two of the three cases, evaluated clinically as complete recovery, and in the other one case, the tumor reduced by 75% in size, evaluated clinically as partial recovery. The total effective rate was 100% and no radioactive damage of irradiation was observed in normal tissues during or after radiotherapy. CONCLUSION: 12C6+ heavy ion beam has the advantage of high accuracy, short course of treatment, and slight lesion of normal tissues round sarcoma, especially in some ray-resistant refractory tumors for conventional radiotherapy.
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