Relationship between DNA degradation in human marrow nuclei and late postmortem interval after death
AIM: To study the relationship between degradation of DNA in human marrow nuclei and estimation of postmortem interval. METHODS: The amount of nuclear DNA in the marrow of sternum was determined from 1 to 10 d after death stained by improved Feulgen histochemical method with image analysis. RESULTS: The content of marrow DNA decreased gradually with the prolongation of postmortem interval and gradated to its minimum after 10 d after death. CONCLUSION: The content of nuclear DNA in human marrow of sternum reduces with extending time and there is a linear relationship between the degradation rate of the nuclear DNA and postmortem interval.
postmortem intervalDNA contentcorrupt corpsemarrow of sternum