An analysis of clinical diagnoses of tuberculous meningitis
AIM: To analyze the clinical diagnoses of tuberculous meningitis. METHODS: Clinical symptoms and auxiliary examinations of 45 patients with tuberculous meningitis and 40 patients with virus meningitis were analyzed retrospectively. RESULTS: The cranial nervous lesions were more common in patients with tuberculous meningitis than patients with virus meningitis (P <0.05 )but no significant differences was seen in fever, headache, vomiting, emotional disturbance, conscious disturbance, meningeal irritation sign and intracranial pressure between the two groups. The positive rate of tuberculin test of tuberculous meningitis was higher than that of virus meningitis ( P < 0. 05 ) but no apparent difference was observed in blood sedimentation rate. The abnormality of the electroencephalogram, cranial computed tomography and magnetic resonance imaging of tuberculous meningitis was higher than that of vires meningitis ( P < 0. 05 ).The protein, immunoglobulin G and immunoglobulin M of cerebrospinal fluid of tuberculous meningitis were higher than those of virus meningitis (P < 0. 05 ). The chloridum of tuberculous meningitis was lower than that of virus meningitis, but with no difference in glucose and immunoglobulin A between the two groups. The percentage of neutrophilic leukocytes and intermix cytology reaction of the tuberculous meningitis were higher than those of virus meningitis( P < 0. 05 ), whereas lymphoid cytology reaction was lower. CONCLUSION: The aggregate analysis of clinical manifestations and auxiliary examinations, especially of cerebrospinad fluid cytology, play very important roles in the clinical diagnosis of tuberculous meningitis.