Electron microscopic diagnosis of gastric leiomyoblastoma
AIM: To determine the role of electron microscopy in the diagnosis of gastric leiomyoblastoma. METHODS: The specimens from surgical or gastroscopy were 1 nun × 1 mm × 1 mm in size. The specimens were fixed by 30 mL/L glutaraldehyde immediately, post-fixed by esmie acid, dehydrated and permeated routinely, embedded by Epoxy resin, and observed with JEM-2000EX transmission electron microscope. RESULTS: The tumor cells arranged in patch and cell junction or junctional complex was seen occasionally between cells. Most of the neoplastic cytoplasms were filled with myofilaments, dense bodies and dense patches. Rough endoplasmic reticulum dilated as lake and a variety of protein secretion of intermediate electron density were found in the dilated cisternae. Intracisternal segregation was also observed. The nucleus were round or oval in shape and anomalistic nucleus were found in part of the cells. CONCLUSION: Eiectron microscopy shows the distinctive features of gastric leiomyoblastorna, which is very helpful for the diagnosis of gastric leiomyoblastoma. Electron microscopy also shows that the clear appearance of tumor cells is the result of the dilation of rough endoplasmic reticulum, not the fat droplets, glycogens or mucus in cytoplasm.
leiomyoma, epithelioiddiagnosismicroscopy, electron
NETL
NSTL
万方数据
维普
