Cellular localization of annexin 5 in rat's digestive organs
AIM:To investigate the cellular distribution of annexin 5 in rat's digestive organs using immunohistochemistry and immunofluorescence. METHODS: Digestive organs from healthy rats were fixed with Bouin's solution. Annexin 5 was examined for its specific distribution in rat digestive organs by immunohistochemistry and immunofluorescence with specific antiserum to rat annexin 5. RESULTS: Annexin 5 was localized in digestive organs of rats in specific cell types. Annexin 5 mainly existed in epithelial cells in stomach,partial cells in fundus glands,goblet cells in small intestine,endothelial cells in bile duct and endothe-lial cells in blood vessel of liver. Annexin 5 was also observed in mucous membrane and muscular layer of stomach and small intestine,lamina propria cells in small intestine,endothelial cells in liver and endothelial cells in blood vessel in pancreas. CONCLUSION: The existence of annexin 5 localized in many cell types with specific function in rat's digestive organs indicates that annexin 5 might be involved in these physiologic functions.
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万方数据
维普
