Clinical efficacy of Q-value adjusted customized laser in situ keratomileusis for high myopia treatment
AIM: To evaluate the efficacy,safety and predictability of Q-value adjusted customized laser in situ keratomileusis (LASIK) for high myopia and astigmatism using an Allegretto Wave Eye-Q platform. METHODS: Eighty-four high myopia eyes (from 42 patients) were enrolled in a controlled study,in which 42 eyes were randomly chosen to be treated with Q-value customized ablation (Q-value adjusted study group) and another eye of the same person was treated with standard Wavefront-opti-mized ablation ( control group). The procedures for both groups were conducted with an Allegretto Wave Eye-Q excimer laser system. Q-value customized ablation was prepared with a scheimpflug topography with the Oculyzer anterior segment imaging system (Wavelight,Inc. ) and F-CAT ablation planning software. The efficacy,safety and predictability were evaluated for a period of 6 months following the surgery. RESULTS: The evaluation at 6 months showed the following results for the Q-value adjusted group and wavefront-optimized group: Safety:No eye lost more than 2 lines of best spectacle-corrected visual acuity (BSCVA) in either group and only 1 eye lost 1 line of BSCVA;Efficacy: UCVA was (5.09 ±0.03 ) and (5.05 ±0.20),with 5.0 or better in 100% in both groups,and 5.1 or better in 57.1% and 52.4%,respectively;Predictability: Postoperative mean spherical equivalent of the manifest refraction ( SE) was ( - 0. 02 ± 0. 56) D and ( -0.09±0.49)D,with all eyes within ±0.75 D of the intended correction,and 84.2% and 83. 6% of the eyes within ±0. 50D of the intended correction,respectively;Q-value: Postoperative Q-value for Q-value adjusted group was (0. 28 ± 0. 36),which required significantly less oblation compared with that required in wavefront-optimized group (0.44 ±0.23). CONCLUSION: A 6-month follow-up indicates that both Q-value customized ablation and standard wavefront-optimized ablation LASIK surgeries show very good safety,efficacy and predictability. The Q-value adjusted treatment appears to be better than wavefront-optimized treatment in terms of maintaining anterior corneal asphericity.
keratomileusis,laser in situQ-valuehigh myopiacorneal asphericity
NETL
NSTL
万方数据
维普
