Electrophysiology changes of midgastric transverse band and near far-end spot of pig stomachs
AIM: To study the role and the mechanism of midgastric transverse band(MTB) in gastric emptying by determining the electrical activity changes of smooth muscles of MTB and near-far spot in fasting and postprandial pigs. METHODS: Under single photon emission computed tomography imnger (SPECT), we tagged MTB in 8 healthy Yorkshire pigs, anesthetired them, opened their abdominal cavity, and then respectively sewed 4 pairs of Ag-AgCl bipolar electrode in serosa layer of the stomach ventral side. E4 was 2 cm from the pylorus, E3 waslocated the midpoint of MTB marked by rods nuclide, E2 was located at the beginning of peristaltic wave and E1 was located at the bottom of the stomach. The electrical activity in the four parts of smooth muscles was recorded by RM6240B multi-channel physiological signal acquisition and processing instrument before and after med. RESULTS: Compared with that of fasting pigs, the slow-wave frequency of each part increased in postprandial pigs (P＜0.05). Compared with those of fasting pigs, no significant changes were observed in the spike frequency, spike peak area and spike-amplitude after med in E1, but significant increase was observed in the spike frequency, the spike peak area and spike amplitude after med in E2 to E4 (P＜0.05 ). The spike frequency, spike peak area and spike amplitude of the same positions increased after med compared with those before med (P＜0.05). The changes were of an increasing tendency, with the changes in E4 were the most remarkable. CONCLUSION: The electrical activity of MTB after med increases compared with that before med, a transition from proximal to distal stomach, indiesring that the changes are not the result of local smooth muscle con-traction.
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NSTL
万方数据
维普
