Botulinum toxin type A for treatment of masseteric hypertrophy: An evaluation with computed tomography and electromyographic measurement
AIM: To evaluate the effects of botulinum toxin type A on the thickness and electromyographic changes in the masseteric muscle using computed tomography and etectromyographic measurement. METHODS: Twenty patients (40 sides) with bilateral maaaetefic hypertrophy were treated with intramuscular injection of botulinum toxin type A, 50 000 U/L for each side. The thickness and electromyographic changes of masseter muscle and complications were recorded at different time points. RESULES: Computed tomography showed that the massetefic thickness of the 20 patients was significantly reduced post-injection compared with that pre-injection (P＜0.01). The maximum reduction was observed from 4th to 12th week after injection, and the strength and the volume of masseter gradually recovered 12 weeks after injection. Though the strength of masseter recovered to normal in most patients 24 weeks after injection, differences were observed in the recovery of masseteric volume. Electromyographic measurement showed that the extent of motor unit potential obviously reduced compared with that pre-injection (P＜0.01). Eighty-five percent of the 20 patients were generally satisfied with the therapeutic results. CONCLUSION: The therapeutic effect of botulinum toxin type A in the treatment of maaseteric hypertrophy can be evaluated by computed tomography and electromyographic measurement.
botulinum toxin type Amasseteric musclecomputed tomographyelectromyographic measurement
NETL
NSTL
万方数据
维普
