Correlation between ultrasensitive Creactive protein and primary nephrotic syndrome
AIM: To investigate the correlation between C-reactive protein (CRP) and primary nephrotic syndrome (PNS). METHODS: Seventy-six patients with PNS and 40 healthy subjects were included in the study. The serum high sensitivity C-reactive protein (hsCRP) and other related indexes were measured and analyzed. RESULTS:The level of hsCRP in patients with PNS was significantly higher than that in control group. Pearson correlation analysis indicated that the hsCRP level was positively correlated with body mass index (BMI), systolic blood pressure (SBP) and diastolic blood pressure (DBP) (P < 0.05). Stepwise linear regression showed a linear correlation between BMI and hsCRP. CONCLUSION: Microinflammation featured by increased hsCRP level exists in patients with PNS, and the hsCRP level is associated with BMI and blood pressure but not with complications of PNS, such as proteinuria, hypoproteinemia and hyperlipoidemia.
nephrotic syndromeC-reactive proteinbody mass indexblood pressure