Study on gene for resistance of carbap-enems in Acinetobacter baumannii
AIM: To study the gene for resistance of carbapenems in Acinetobacter baumannii. METHODS: Drug susceptibility was determined by K-B and the fragment of BLA vim, BLA imp, OXA-23 and OXA-24 genes were amplified by polymerase chain reactions. RESULTS: In the 12 strains of lipenem-resistant Acinetobacter baumannii, the fragment of BLA vim, OXA-23 genes was amplified simultaneously from 3 strains and the fragment of OXA-23 gene was amplified from 7 strains. The gene coding drug resistance was lost in the other 2 strains. CONCLUSION: Some Iipenem-resistant Acinetobacter baumannii which produce metallo-β-lactamase carry not only BAL vim gene coding metallo-β-lactamase but also some other drug resistant genes.
NETL
NSTL
万方数据
维普
